| The
"Associazione Marta Nurizzo"
born on July 11, 1996, takes its name after Marta, died on
May 11, 1995 at the age of 21, owing to a bronchial-alveolar
carcinoma.
The Associazione is a no-profit
organization, recognized by the Italian Ministry
for University and Scientific Research, aiming at promoting
the research on lung cancer. It collects
funds from supporters, private people and
companies to grant research projects and fellowships in this
field; promotional and cultural events are also organized
for fund raising.
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The second fellowship (1998)
of the same amount was assigned to dr.
F. Crosti. Her research
project "Genetic susceptibility
and environmental carcinogens in lung cancer",
started at the Nelson Institute of Epidemiological Medicine, New York Medical Center, New York University,
USA. The Associazione’s Scientific Committee, after
the first quarterly check, suggested stopping the project
since the local situation appeared not to be worth for the
fellow.
From
the beginning of the new millenium,
the Associazione has focused its activity on the research
project "Genetic predisposition
to lung cancer", currently developed
together with the "Istituto Nazionale per lo Studio e
la Cura dei Tumori", Milano (Italian National Cancer
Institute, Milan) and the "Istituto di Ricerca Farmacologica
Mario Negri", Milano (“Mario Negri” Pharmacological
Research Institute, Milan). The research is aimed at investigating
the genetic elements affecting lung cancer risk: the main
target is therefore to collect the largest possible number
of blood samples coming from patients under 60 who never smoked
and, possibly, from their healthy relatives (brothers or sisters
or parents). Till now, more than 200 patients’ samples
and more than 165 control samples were collected and analyzed.
Among them, 115 couples of samples (patient and brother/sister,
having less than 60 years) were extracted to more deeply study
the metabolic polymorphisms.
At the end of 2007 a new call for a 18,000
€ fellowship (plus up to 5,000 € for stages and
extra scientific activities) was made and the winner was dr.
S. La Monica of the Parma University. Her research
project was titled “Study
of the resistance mechanisms to EGFR inhibitors in cellular
lines of non small cell lung cancer”;
at the end of 2008 the fellowship was renewed
to allow the completion of the research at the Department
of Experimental Medicine, Molecular Pathology and Immunology
Section of the Parma University.
At
present the 2010 "Marta
Nurizzo" fellowship (20,000 €, plus
an extra possible contribution of 4,000 €) is supporting
the research of dr. F. Colombo. Her research
project "Functional
characterization of candidate genes associated with lung cancer
prognosis"
is taking place at the Italian National Cancer Institute,
Milano.
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